Endocrine Abstracts

Introduction: Early detection of congenital hypothyroidism (CHT), and treatment with oral thyroxine, supports the critical period of early brain development, improves growth and prevents the metabolic effects of adult hypothyroidism. Screening for CHT, involving an assay for thyroid-stimulating hormone (TSH), has been included in the UK newborn blood spot screening programme since 1981. Since the introduction of screening, the number of CHT cases has increased, although the re...

Introduction: Congenital adrenal hyperplasia (CAH) is a rare condition affecting steroid-hormone synthesis. We reviewed the investigation and management of children with CAH against current international guidelines and explored variation by region and specialty of responsible clinician.Methods: Active national surveillance of new diagnoses of CAH in children under age 16 years and resident in Great Britain, undertaken prospectively from 2007 to 2009....